Constructed in comic-book like fashion, You Killed Me on the Moon is about being shot down when you are figuratively high above the earth's atmosphere. 
 
After all, beating impossible odds is a Toy Story right? There is a saying that sometimes the person you would take a bullet for is the one who will shoot you with one. This piece is also inspired by a song from the Blow, with the same title - "You Killed Me on the Moon."